Culturing of mammalian cells expressing recombinant connexins and two-dimensional crystallization of the isolated gap junctions.
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چکیده
منابع مشابه
Upregulation of Connexins 30 and 32 Gap Junctions in Rat Hippocampus at Transcription Level by Chronic Central Injection of Lipopolysaccharide
Background: Gap junctions composed of connexins (Cx) are functional in cell defense by propagation of toxic/death molecules to neighboring cells. Hippocampus, one of the brain regions with particular vulnerability to damage, has a wide network of gap junctions. Functional response of astrocytic Cx30 and neuronal Cx32 to hippocampal damage is unknown. Methods: We infused lipopolysaccharide (LPS)...
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Introduction: Gap junctions are intercellular membrane channels that provide direct cytoplasmic continuity between adjacent cells. This communication can be affected by changes in expression of gap junctional subunits called Connexins (Cx). Changes in the expression and function of connexins are associated with number of brain neurodegenerative diseases. Neuroinflammation is a hallmark of vario...
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ورودعنوان ژورنال:
- Methods in molecular biology
دوره 154 شماره
صفحات -
تاریخ انتشار 2001